PRR12

Across TCGA patient cohorts, PRR12 mutation is significantly associated with the RNA expression of many other genes, with 3,274 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR12-associated genes across cancer lineages are H2AZ1, LINC01635, and PHF5A. Each is linked with PRR12 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRR12-to-partner and partner-to-PRR12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H2AZ1 grouped by PRR12-low versus PRR12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR12→partner) and Y-score (partner→PRR12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	H2AZ1 →	+0.488	+1.942	.001	.002	3	4
SKCM	LINC01635 →	+0.367	+2.515	<.001	.001	3	4
UCEC	PHF5A →	+0.359	+3.098	.002	<.001	3	4
UCEC	RPL23AP82 →	+0.319	+1.332	.001	.008	3	4
LIHC	NDUFA3P3 →	+0.067	+4.676	<.001	.004	3	3
COAD	CENPM →	+0.643	+2.392	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,274 associations by consensus.

H2AZ1 by PRR12 expression — UCEC

Explore this box plot interactively →