PRR12

Across TCGA cell cohorts, PRR12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,874 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PRR12-associated GO terms across cancer lineages are mRNA alternative polyadenylation, Negative regulation of calcium ion export across plasma membrane, and Negative regulation of DNA-templated transcription, elongation. Each is linked with PRR12 in more than 18 cancer types. Because this analysis shows association rather than direction, both PRR12-to-partner and partner-to-PRR12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA alternative polyadenylation grouped by PRR12-low versus PRR12-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR12→partner) and Y-score (partner→PRR12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	mRNA alternative polyadenylation →	+0.120	+1.281	<.001	.001	3	19
OESOPHAGUS	Negative regulation of calcium ion export across plasma membrane →	+0.089	+0.864	.006	.004	3	19
SOFT_TISSUE	Negative regulation of DNA-templated transcription, elongation →	+0.103	+0.808	<.001	<.001	3	17
OESOPHAGUS	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.215	+0.973	<.001	.002	3	17
BONE	Epigenetic regulation of gene expression →	+0.108	+1.492	<.001	<.001	3	17
OESOPHAGUS	Transcription initiation-coupled chromatin remodeling →	+0.108	+0.887	<.001	.007	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,874 associations by consensus.

mRNA alternative polyadenylation by PRR12 expression — STOMACH

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