PRR12

Across TCGA cell cohorts, PRR12 mutation is significantly associated with the RNA expression of many other genes, with 2,018 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PRR12-associated genes across cancer lineages are RTP5, CCDC113, and UAP1. Each is linked with PRR12 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRR12-to-partner and partner-to-PRR12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RTP5 grouped by PRR12-low versus PRR12-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR12→partner) and Y-score (partner→PRR12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RTP5 →	+0.620	+1.984	<.001	.004	3	3
LARGE_INTESTINE	CCDC113 →	+0.756	+3.321	.001	.002	3	3
LARGE_INTESTINE	UAP1 →	+0.540	+2.364	.001	<.001	3	3
LARGE_INTESTINE	GDPGP1 →	+0.537	+2.364	.001	<.001	3	3
LARGE_INTESTINE	NF2 →	+0.647	+1.850	.001	.006	3	3
PANCREAS	CPXCR1 →	+0.031	+3.724	.006	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,018 associations by consensus.

RTP5 by PRR12 expression — BLOOD_Leukemia

Explore this box plot interactively →