PRPS1P2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PRPS1P2 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated PRPS1P2 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PRPS1P2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PRPS1P2 expression acts as an unfavorable survival marker, although some lineages such as SKCM and PAAD show a favorable association.

STAD, SKCM, and MESO are the cancer types where PRPS1P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADDFSTertileIII,IV0.3020.668<.00159view →
SKCMOSMedianIII,IV0.5020.283.00239view →
MESODFSMedianAll0.2350.611.00230view →
KIRCDFSMedianAll0.7660.841.01729view →
PAADOSMedianAll0.5760.332.00227view →
CESCDFSQuartileIII,IV0.2260.932.00324view →
UCSDFSTertileIII,IV0.3960.137.02520view →
BLCADFSTertileAll0.1940.553.00119view →
ESCAOSMedianIV0.2220.698.00618view →
COADOSMedianAll0.7320.870.00416view →
THCAOSQuartileII,III,IV0.7231.000.00315view →
LUSCDFSTertileIII,IV0.6851.000.01615view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

PRPS1P2–STAD (DFS)

Kaplan–Meier survival curve for PRPS1P2 RNA-high vs -low samples in STAD.

Open the STAD breakdown →

Exploration