Across TCGA patient cohorts, PRPS1L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,263 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRPS1L1-associated GO terms across cancer lineages are Regulation of microtubule cytoskeleton organization, Telomere maintenance, and Regulation of microtubule-based process. Each is linked with PRPS1L1 in more than 15 cancer types. Because this analysis shows association rather than direction, both PRPS1L1-to-partner and partner-to-PRPS1L1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPS1L1→partner) and Y-score (partner→PRPS1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of microtubule cytoskeleton organization →	+0.042	+0.092	<.001	<.001	3	16
STAD	Telomere maintenance →	+0.051	+0.110	<.001	<.001	3	14
ESCA	Regulation of microtubule-based process →	+0.046	+0.126	<.001	.002	3	14
ESCA	Positive regulation of post-translational protein modification →	+0.048	+0.142	.006	.002	3	13
STAD	Regulation of double-strand break repair →	+0.048	+0.107	<.001	<.001	3	13
ESCA	Positive regulation of chromosome organization →	+0.062	+0.170	.006	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,263 associations by consensus.

Exploration

PRPS1L1 survival (RNA) · tumor vs normal (RNA) · all PRPS1L1 data types