PRPH2

Across TCGA cell cohorts, PRPH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 951 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PRPH2-associated GO terms across cancer lineages are Positive regulation of calcium ion transmembrane transport, Cellular detoxification of methylglyoxal, and Response to methylglyoxal. Each is linked with PRPH2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRPH2-to-partner and partner-to-PRPH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of calcium ion transmembrane transport grouped by PRPH2-low versus PRPH2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPH2→partner) and Y-score (partner→PRPH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of calcium ion transmembrane transport →	-0.128	-1.050	.001	.003	3	5
LUNG_NSCLC_LUSC	Cellular detoxification of methylglyoxal →	+0.147	+0.054	<.001	.001	3	4
LUNG_NSCLC_LUSC	Response to methylglyoxal →	+0.147	+0.054	<.001	.001	3	4
LUNG_NSCLC_LUSC	Cellular response to methylglyoxal →	+0.147	+0.054	<.001	.001	3	4
SOFT_TISSUE	Response to light intensity →	-0.158	-1.153	<.001	<.001	3	4
LARGE_INTESTINE	Positive regulation of transcription initiation by RNA polymerase II →	+0.058	+0.040	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 951 associations by consensus.

Positive regulation of calcium ion transmembrane transport by PRPH2 expression — SOFT_TISSUE

Explore this box plot interactively →