PRPF6

Across TCGA patient cohorts, PRPF6 protein abundance is significantly associated with the RNA expression of many other genes, with 18,474 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRPF6-associated genes across cancer lineages are RAE1, NELFCD, and CSTF1. Each is linked with PRPF6 in more than 8 cancer types. Because this analysis shows association rather than direction, both PRPF6-to-partner and partner-to-PRPF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRPF6 versus RAE1 in OV, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF6→partner) and Y-score (partner→PRPF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RAE1 →	+0.706	+0.201	<.001	.002	3	9
HNSC	NELFCD →	+0.839	+0.188	<.001	<.001	3	9
OV	CSTF1 →	+0.541	+0.282	<.001	<.001	3	8
COAD	MOCS3 →	+0.539	+0.137	<.001	<.001	3	8
UCEC	DDX27 →	+0.638	+0.227	<.001	<.001	3	8
UCEC	LSM14B →	+0.738	+0.237	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,474 associations by consensus.

PRPF6 vs RAE1 — OV

Explore this scatter interactively →