PRPF4B

Across TCGA patient cohorts, PRPF4B protein abundance is significantly associated with the RNA expression of many other genes, with 17,936 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRPF4B-associated genes across cancer lineages are NUP153, BPHL, and ZSCAN16. Each is linked with PRPF4B in more than 7 cancer types. Because this analysis shows association rather than direction, both PRPF4B-to-partner and partner-to-PRPF4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRPF4B versus NUP153 in LSCC, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF4B→partner) and Y-score (partner→PRPF4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NUP153 →	+0.698	+0.290	<.001	<.001	3	8
HNSC	BPHL →	+0.677	+0.279	<.001	<.001	3	8
HNSC	ZSCAN16 →	+0.643	+0.164	<.001	<.001	3	8
COAD	NELFCD →	+0.677	+0.182	<.001	<.001	3	7
LSCC	TGIF2 →	+0.755	+0.308	<.001	<.001	3	7
LSCC	XPO5 →	+0.745	+0.277	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,936 associations by consensus.

PRPF4B vs NUP153 — LSCC

Explore this scatter interactively →