PRPF4B

Across TCGA cell cohorts, PRPF4B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,964 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRPF4B-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, Negative regulation of nucleobase-containing compound transport, and Epigenetic regulation of gene expression. Each is linked with PRPF4B in more than 19 cancer types. Because this analysis shows association rather than direction, both PRPF4B-to-partner and partner-to-PRPF4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA export from nucleus grouped by PRPF4B-low versus PRPF4B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF4B→partner) and Y-score (partner→PRPF4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of RNA export from nucleus →	+0.187	+0.761	<.001	<.001	3	20
BONE	Negative regulation of nucleobase-containing compound transport →	+0.195	+0.875	.002	<.001	3	18
SOFT_TISSUE	Epigenetic regulation of gene expression →	+0.068	+0.772	<.001	<.001	3	18
OESOPHAGUS	Regulation of mRNA stability →	+0.068	+0.947	.001	.002	3	17
LIVER	DNA-templated DNA replication maintenance of fidelity →	+0.092	+0.821	.008	.001	2	18
BLOOD_Myeloma	DNA-templated DNA replication →	+0.133	+0.671	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,964 associations by consensus.

Negative regulation of RNA export from nucleus by PRPF4B expression — STOMACH

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