Across TCGA patient cohorts, PRPF40A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,142 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRPF40A-associated proteins across cancer lineages are RIF1, ILKAP, and U2AF2. Each is linked with PRPF40A in more than 6 cancer types. Because this analysis shows association rather than direction, both PRPF40A-to-partner and partner-to-PRPF40A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF40A→partner) and Y-score (partner→PRPF40A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RIF1 →	+0.418	+0.551	<.001	<.001	3	7
GBM	ILKAP →	+0.254	+0.222	<.001	<.001	3	7
GBM	U2AF2 →	+0.286	+0.339	<.001	<.001	3	6
LSCC	HAT1 →	+0.323	+0.339	<.001	<.001	3	6
GBM	OGFOD1 →	+0.432	+0.328	<.001	<.001	3	6
OV	ORC4 →	+0.302	+0.503	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,142 associations by consensus.

Exploration

PRPF40A survival (RNA) · tumor vs normal (RNA) · all PRPF40A data types