Across TCGA patient cohorts, PRPF40A protein abundance is significantly associated with the RNA expression of many other genes, with 17,019 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRPF40A-associated genes across cancer lineages are PIF1, SNHG1, and NCAPD2. Each is linked with PRPF40A in more than 7 cancer types. Because this analysis shows association rather than direction, both PRPF40A-to-partner and partner-to-PRPF40A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF40A→partner) and Y-score (partner→PRPF40A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIF1 →	+1.089	+0.168	<.001	.001	3	8
HNSC	SNHG1 →	+0.778	+0.175	.002	<.001	3	8
HNSC	NCAPD2 →	+0.876	+0.146	<.001	<.001	3	7
HNSC	NUP85 →	+0.688	+0.163	.008	.002	3	7
UCEC	PDCD2L →	+0.636	+0.167	.002	<.001	3	7
UCEC	PARP2 →	+0.684	+0.165	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,019 associations by consensus.

Exploration

PRPF40A survival (RNA) · tumor vs normal (RNA) · all PRPF40A data types