Across TCGA cell cohorts, PRPF40A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,742 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRPF40A-associated GO terms across cancer lineages are Replication fork processing, Double-strand break repair, and Microtubule organizing center organization. Each is linked with PRPF40A in more than 16 cancer types. Because this analysis shows association rather than direction, both PRPF40A-to-partner and partner-to-PRPF40A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF40A→partner) and Y-score (partner→PRPF40A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Replication fork processing →	+0.136	+0.931	.004	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.067	+0.803	<.001	<.001	3	17
BONE	Microtubule organizing center organization →	+0.082	+0.861	.008	.001	3	17
UPPER_AERODIGESTIVE_TRACT	Recombinational repair →	+0.075	+0.701	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of G2/M transition of mitotic cell cycle →	+0.071	+0.618	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Late viral transcription →	+0.128	+1.014	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,742 associations by consensus.

Exploration

PRPF40A survival (RNA) · tumor vs normal (RNA) · all PRPF40A data types