PRPF4

Across TCGA patient cohorts, PRPF4 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,730 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRPF4-associated proteins across cancer lineages are RRM1, SMC2, and NASP. Each is linked with PRPF4 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRPF4-to-partner and partner-to-PRPF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRPF4 versus RRM1 in GBM, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF4→partner) and Y-score (partner→PRPF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RRM1 →	+0.640	+0.432	<.001	<.001	3	8
LSCC	SMC2 →	+0.703	+0.844	<.001	<.001	3	8
GBM	NASP →	+0.516	+0.273	<.001	<.001	3	7
LSCC	TEX10 →	+0.414	+0.881	<.001	<.001	3	7
LUAD	TRAF2 →	+0.308	+0.322	.001	.003	3	7
HNSC	ELP1 →	+0.269	+0.685	<.001	<.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,730 associations by consensus.

PRPF4 vs RRM1 — GBM

Explore this scatter interactively →