PRPF38A

Across TCGA patient cohorts, PRPF38A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,652 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRPF38A-associated proteins across cancer lineages are THOC1, RNF220, and RSBN1. Each is linked with PRPF38A in more than 6 cancer types. Because this analysis shows association rather than direction, both PRPF38A-to-partner and partner-to-PRPF38A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRPF38A versus THOC1 in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF38A→partner) and Y-score (partner→PRPF38A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	THOC1 →	+0.242	+0.395	.001	<.001	3	7
PDAC	RNF220 →	+0.364	+0.266	.001	<.001	3	6
UCEC	RSBN1 →	+0.303	+0.314	<.001	.002	3	6
GBM	SF3B3 →	+0.207	+0.365	<.001	<.001	3	6
GBM	THOC5 →	+0.340	+0.430	<.001	<.001	3	6
GBM	HPF1 →	+0.301	+0.333	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,652 associations by consensus.

PRPF38A vs THOC1 — LSCC

Explore this scatter interactively →