PRPF38A

Across TCGA patient cohorts, PRPF38A protein abundance is significantly associated with the RNA expression of many other genes, with 14,780 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRPF38A-associated genes across cancer lineages are MMS22L, RPS17, and CCNB1IP1. Each is linked with PRPF38A in more than 5 cancer types. Because this analysis shows association rather than direction, both PRPF38A-to-partner and partner-to-PRPF38A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRPF38A versus MMS22L in GBM, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF38A→partner) and Y-score (partner→PRPF38A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MMS22L →	+0.654	+0.262	<.001	<.001	3	6
LSCC	RPS17 →	+0.488	+0.185	<.001	<.001	3	6
HNSC	CCNB1IP1 →	+0.758	+0.192	.004	.005	3	5
GBM	KAT2A →	+0.673	+0.267	<.001	<.001	3	5
LSCC	LUC7L3 →	+0.530	+0.179	<.001	<.001	3	5
HNSC	CPSF6 →	+0.537	+0.136	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,780 associations by consensus.

PRPF38A vs MMS22L — GBM

Explore this scatter interactively →