PRPF3

Across TCGA patient cohorts, PRPF3 protein abundance is significantly associated with the RNA expression of many other genes, with 19,996 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRPF3-associated genes across cancer lineages are CENPL, MRPL9, and CKS1B. Each is linked with PRPF3 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRPF3-to-partner and partner-to-PRPF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRPF3 versus CENPL in UCEC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRPF3→partner) and Y-score (partner→PRPF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPL →	+0.821	+0.296	<.001	<.001	3	8
HNSC	MRPL9 →	+0.795	+0.173	.001	<.001	3	8
UCEC	CKS1B →	+1.061	+0.232	<.001	<.001	3	8
UCEC	EXO1 →	+1.076	+0.260	<.001	<.001	3	8
GBM	FBXO5 →	+0.956	+0.381	<.001	<.001	3	7
HNSC	DARS2 →	+0.768	+0.226	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,996 associations by consensus.

PRPF3 vs CENPL — UCEC

Explore this scatter interactively →