PROX2

Across TCGA patient cohorts, PROX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,810 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PROX2-associated proteins across cancer lineages are PPP4R3A, NEK9, and UBR7. Each is linked with PROX2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PROX2-to-partner and partner-to-PROX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PROX2 versus PPP4R3A in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PROX2→partner) and Y-score (partner→PROX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPP4R3A →	+0.269	+0.293	<.001	<.001	3	6
BRCA	NEK9 →	+0.262	+0.289	<.001	<.001	3	6
LSCC	UBR7 →	+0.394	+0.341	<.001	<.001	3	6
GBM	YLPM1 →	+0.340	+0.721	<.001	<.001	3	6
LUAD	GFPT1 →	-0.369	-0.449	<.001	<.001	3	6
GBM	APEX1 →	+0.326	+0.456	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,810 associations by consensus.

PROX2 vs PPP4R3A — LSCC

Explore this scatter interactively →