PRORP

Across TCGA cell cohorts, PRORP protein abundance is significantly associated with the RNA expression of many other genes, with 1,427 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible PRORP-associated genes across cancer lineages are ZDHHC2, C9orf72, and NUDCD2. Each is linked with PRORP in more than 3 cancer types. Because this analysis shows association rather than direction, both PRORP-to-partner and partner-to-PRORP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRORP versus ZDHHC2 in LIVER, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRORP→partner) and Y-score (partner→PRORP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	ZDHHC2 →	-1.348	-0.586	.001	.003	3	4
LIVER	C9orf72 →	-0.820	-0.574	.006	.004	3	4
LIVER	NUDCD2 →	-1.028	-0.617	<.001	.001	3	4
OESOPHAGUS	NUBPL →	+1.380	+1.762	.004	<.001	3	4
BLOOD_Leukemia	ZNF397 →	-1.031	-0.978	<.001	.004	3	4
LUNG_NSCLC_LUSC	CACFD1 →	-1.585	-1.350	.002	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,427 associations by consensus.

PRORP vs ZDHHC2 — LIVER

Explore this scatter interactively →