PROKR1

Across TCGA patient cohorts, PROKR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,085 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible PROKR1-associated GO terms across cancer lineages are Maintenance of cell number, Golgi organization, and Regulation of microtubule cytoskeleton organization. Each is linked with PROKR1 in more than 24 cancer types. Because this analysis shows association rather than direction, both PROKR1-to-partner and partner-to-PROKR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of cell number grouped by PROKR1-low versus PROKR1-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PROKR1→partner) and Y-score (partner→PROKR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Maintenance of cell number →	+0.067	+1.315	.001	.006	3	24
STAD	Golgi organization →	+0.083	+0.092	<.001	<.001	3	24
STAD	Regulation of microtubule cytoskeleton organization →	+0.071	+0.090	<.001	<.001	2	25
STAD	DNA-templated transcription initiation →	+0.074	+0.094	<.001	<.001	3	23
SCLC	Protein-containing complex disassembly →	+0.079	+1.186	<.001	<.001	2	24
SCLC	Negative regulation of cytoskeleton organization →	+0.064	+0.970	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,085 associations by consensus.

Maintenance of cell number by PROKR1 expression — SCLC

Explore this box plot interactively →