PROKR1

Across TCGA cell cohorts, PROKR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,617 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PROKR1-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with PROKR1 in more than 10 cancer types. Because this analysis shows association rather than direction, both PROKR1-to-partner and partner-to-PROKR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by PROKR1-low versus PROKR1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PROKR1→partner) and Y-score (partner→PROKR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of myoblast fusion →	+0.107	+0.052	<.001	<.001	3	11
OVARY	Negative regulation of myoblast fusion →	+0.078	+0.035	<.001	<.001	3	10
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.080	+0.037	<.001	<.001	3	10
PANCREAS	Regulation of DNA-templated transcription elongation →	+0.058	+0.039	<.001	.007	2	10
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.105	+0.052	<.001	<.001	3	9
PANCREAS	Establishment of protein localization to organelle →	+0.055	+0.073	<.001	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,617 associations by consensus.

Regulation of myoblast fusion by PROKR1 expression — OVARY

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