PROK2

Across TCGA cell cohorts, PROK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,467 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PROK2-associated GO terms across cancer lineages are Nephron development, snRNA metabolic process, and Nerve development. Each is linked with PROK2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PROK2-to-partner and partner-to-PROK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nephron development grouped by PROK2-low versus PROK2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PROK2→partner) and Y-score (partner→PROK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nephron development →	-0.078	-1.319	<.001	<.001	3	5
BONE	snRNA metabolic process →	+0.072	+1.335	.003	.001	3	5
BONE	Nerve development →	-0.106	-1.613	.007	<.001	3	5
BLOOD_Leukemia	Sensory perception of sound →	-0.032	-1.560	.002	.001	3	5
CNS	Regulation of Rho protein signal transduction →	-0.065	-0.374	<.001	.005	3	4
BONE	Ribose phosphate biosynthetic process →	+0.091	+1.370	.002	.009	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,467 associations by consensus.

Nephron development by PROK2 expression — BONE

Explore this box plot interactively →