PRODH2

Across TCGA cell cohorts, PRODH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 515 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible PRODH2-associated GO terms across cancer lineages are Positive regulation of glycoprotein metabolic process, Fatty acid oxidation, and Low-density lipoprotein particle remodeling. Each is linked with PRODH2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRODH2-to-partner and partner-to-PRODH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of glycoprotein metabolic process grouped by PRODH2-low versus PRODH2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRODH2→partner) and Y-score (partner→PRODH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of glycoprotein metabolic process →	+0.160	+2.619	.002	.001	3	3
LIVER	Fatty acid oxidation →	+0.101	+3.466	<.001	<.001	3	3
LIVER	Low-density lipoprotein particle remodeling →	+1.324	+2.295	.001	.007	3	3
LIVER	Lipid oxidation →	+0.096	+2.903	<.001	.007	3	3
LIVER	Renal D-glucose absorption →	+1.755	+3.153	<.001	<.001	3	3
BREAST	Male gonad development →	-0.094	-0.036	<.001	.008	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 515 associations by consensus.

Positive regulation of glycoprotein metabolic process by PRODH2 expression — LIVER

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