PROCR

Across TCGA pan-cancer cohorts, PROCR Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PROCR data layer compared with 23 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher PROCR Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated PROCR expression acts as an unfavorable survival marker.

CESC, LIHC, and LUSC are the cancer types where PROCR Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	All	0.172	0.742	<.001	12	view →
LIHC	DFS	Median	All	0.044	0.553	<.001	12	view →
LUSC	DFS	Median	All	0.165	0.660	.036	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PROCR–CESC (DFS)

Open the CESC breakdown →