PROCA1

Across TCGA cell cohorts, PROCA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,676 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PROCA1-associated GO terms across cancer lineages are Protein localization to cytoplasmic stress granule, Base-excision repair, gap-filling, and Pre-mRNA catabolic process. Each is linked with PROCA1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PROCA1-to-partner and partner-to-PROCA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cytoplasmic stress granule grouped by PROCA1-low versus PROCA1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PROCA1→partner) and Y-score (partner→PROCA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Protein localization to cytoplasmic stress granule →	+0.125	+1.046	<.001	<.001	3	15
URINARY_TRACT	Base-excision repair, gap-filling →	+0.122	+1.553	<.001	<.001	3	14
BONE	Pre-mRNA catabolic process →	+0.176	+1.194	<.001	<.001	3	14
BONE	Chiasma assembly →	+0.244	+1.093	.003	.004	3	13
SOFT_TISSUE	Regulation of RNA splicing →	+0.071	+1.017	.001	.002	2	14
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.129	+1.537	.003	<.001	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,676 associations by consensus.

Protein localization to cytoplasmic stress granule by PROCA1 expression — OVARY

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