PRND

Across TCGA cell cohorts, PRND RNA expression is significantly associated with the go_rna of many other GO terms, with 1,053 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRND-associated GO terms across cancer lineages are Bile acid signaling pathway, Sulfur amino acid biosynthetic process, and L-methionine biosynthetic process. Each is linked with PRND in more than 3 cancer types. Because this analysis shows association rather than direction, both PRND-to-partner and partner-to-PRND results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bile acid signaling pathway grouped by PRND-low versus PRND-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRND→partner) and Y-score (partner→PRND) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Bile acid signaling pathway →	+0.234	+1.349	<.001	<.001	3	4
BONE	Sulfur amino acid biosynthetic process →	+0.116	+1.270	.001	<.001	3	3
BONE	L-methionine biosynthetic process →	+0.202	+1.748	<.001	<.001	3	3
BONE	Regulation of triglyceride catabolic process →	-0.162	-1.425	<.001	.006	3	3
BONE	Positive regulation of sodium ion transmembrane transport →	-0.210	-1.447	.002	.003	3	3
BONE	Intracellular nitric oxide homeostasis →	+0.100	+1.298	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,053 associations by consensus.

Bile acid signaling pathway by PRND expression — BONE

Explore this box plot interactively →