PRMT7

Across TCGA cell cohorts, PRMT7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,879 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PRMT7-associated GO terms across cancer lineages are Metaphase/anaphase transition of mitotic cell cycle, Regulation of chromosome organization, and Regulation of establishment of protein localization to chromosome. Each is linked with PRMT7 in more than 15 cancer types. Because this analysis shows association rather than direction, both PRMT7-to-partner and partner-to-PRMT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metaphase/anaphase transition of mitotic cell cycle grouped by PRMT7-low versus PRMT7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT7→partner) and Y-score (partner→PRMT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Metaphase/anaphase transition of mitotic cell cycle →	+0.205	+0.945	.002	<.001	3	16
BONE	Regulation of chromosome organization →	+0.120	+1.001	.002	<.001	3	16
BONE	Regulation of establishment of protein localization to chromosome →	+0.161	+0.982	<.001	<.001	3	16
SOFT_TISSUE	RNA export from nucleus →	+0.121	+0.770	<.001	.001	3	15
BONE	Negative regulation of chromosome organization →	+0.115	+0.919	.004	<.001	3	15
BONE	Positive regulation of DNA metabolic process →	+0.100	+0.907	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,879 associations by consensus.

Metaphase/anaphase transition of mitotic cell cycle by PRMT7 expression — BONE

Explore this box plot interactively →