PRMT7

Across TCGA cell cohorts, PRMT7 mutation is significantly associated with the mutation status of many other genes, with 6,075 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PRMT7-associated genes across cancer lineages are BOD1L1, TDRD6, and PANK4. Each is linked with PRMT7 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRMT7-to-partner and partner-to-PRMT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BOD1L1 grouped by PRMT7-low versus PRMT7-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT7→partner) and Y-score (partner→PRMT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	BOD1L1 →	+2.647	+3.618	.003	.003	1	4
BLOOD_Lymphoma	TDRD6 →	+3.162	+4.016	.001	.001	1	4
SKIN	PANK4 →	+4.392	+4.392	.009	.009	1	4
BLOOD_Leukemia	COL18A1 →	+3.975	+5.498	<.001	<.001	1	4
BLOOD_Leukemia	ROR1 →	+4.560	+4.309	.007	.007	1	4
LARGE_INTESTINE	ERCC4 →	+3.208	+2.736	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,075 associations by consensus.

BOD1L1 by PRMT7 expression — BLOOD_Lymphoma

Explore this box plot interactively →