Across TCGA patient cohorts, PRMT6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,492 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRMT6-associated proteins across cancer lineages are GTF3C4, ZNF326, and BEND3. Each is linked with PRMT6 in more than 5 cancer types. Because this analysis shows association rather than direction, both PRMT6-to-partner and partner-to-PRMT6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT6→partner) and Y-score (partner→PRMT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GTF3C4 →	+0.330	+0.518	.004	.001	3	6
HNSC	ZNF326 →	+0.375	+0.698	<.001	<.001	3	5
LSCC	BEND3 →	+0.267	+0.414	<.001	<.001	3	5
LSCC	BPTF →	+0.366	+0.581	<.001	<.001	3	5
GBM	ADNP →	+0.343	+0.299	<.001	<.001	3	5
GBM	CSTF3 →	+0.268	+0.322	.002	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,492 associations by consensus.

Exploration

PRMT6 survival (RNA) · tumor vs normal (RNA) · all PRMT6 data types