Across TCGA patient cohorts, PRMT6 protein abundance is significantly associated with the RNA expression of many other genes, with 4,111 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRMT6-associated genes across cancer lineages are TTLL5, NUP85, and ATXN7L2. Each is linked with PRMT6 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRMT6-to-partner and partner-to-PRMT6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT6→partner) and Y-score (partner→PRMT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TTLL5 →	+0.504	+0.551	<.001	<.001	3	3
BRCA	NUP85 →	+0.518	+0.477	<.001	<.001	3	3
GBM	ATXN7L2 →	+0.561	+0.425	<.001	.002	3	3
LSCC	GLMN →	+0.479	+0.481	.001	<.001	3	3
BRCA	AURKB →	+0.979	+0.316	<.001	.003	3	3
BRCA	ALYREF →	+0.469	+0.293	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,111 associations by consensus.

Exploration

PRMT6 survival (RNA) · tumor vs normal (RNA) · all PRMT6 data types