PRMT6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRMT6 mutation is significantly associated with the RNA expression of many other genes, with 3,490 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRMT6-associated genes across cancer lineages are E2F6P1, RNA5SP84, and RNA5SP421. Each is linked with PRMT6 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRMT6-to-partner and partner-to-PRMT6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT6→partner) and Y-score (partner→PRMT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCE2F6P1 →+0.031+5.584<.001.00133
BLCARNA5SP84 →+0.208+5.307<.001.00133
KIRPRNA5SP421 →+0.333+7.124<.001<.00132
UCECCKLF →+0.878+2.263<.001<.00132
UCECFANCG →+0.647+2.665<.001<.00132
COADHSBP1L1 →+0.596+3.459<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,490 associations by consensus.

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