Across TCGA cell cohorts, PRMT6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,382 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PRMT6-associated GO terms across cancer lineages are Spliceosomal snRNP assembly, Positive regulation of mRNA processing, and RNA localization. Each is linked with PRMT6 in more than 12 cancer types. Because this analysis shows association rather than direction, both PRMT6-to-partner and partner-to-PRMT6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT6→partner) and Y-score (partner→PRMT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Spliceosomal snRNP assembly →	+0.096	+0.994	.001	.002	3	13
SOFT_TISSUE	Positive regulation of mRNA processing →	+0.128	+0.784	.002	.005	3	12
BONE	RNA localization →	+0.126	+0.972	<.001	.002	3	12
BONE	Double-strand break repair via homologous recombination →	+0.077	+0.852	.005	.002	3	12
OVARY	U2-type prespliceosome assembly →	+0.098	+0.822	.001	.002	3	12
BLOOD_Lymphoma	Epigenetic regulation of gene expression →	+0.065	+1.484	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,382 associations by consensus.

Exploration

PRMT6 survival (RNA) · tumor vs normal (RNA) · all PRMT6 data types