PRMT3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRMT3 mutation is significantly associated with the RNA expression of many other genes, with 2,129 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRMT3-associated genes across cancer lineages are CCL18, SLC7A7, and C1QC. Each is linked with PRMT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRMT3-to-partner and partner-to-PRMT3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT3→partner) and Y-score (partner→PRMT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCCL18 →+1.587+4.008<.001<.00132
UCECSLC7A7 →+0.709+4.135<.001<.00132
UCECC1QC →+1.207+3.700<.001.00132
UCECNOL6 →+0.447+3.413.001<.00132
UCECRRM1 →+0.830+2.736<.001<.00132
UCECLMNB2 →+0.545+3.008.004<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,129 associations by consensus.

Exploration