Across TCGA cell cohorts, PRMT3 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PRMT3-associated genes across cancer lineages are PRRG3, HTR2C, and ZIC3. Each is linked with PRMT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRMT3-to-partner and partner-to-PRMT3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT3→partner) and Y-score (partner→PRMT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PRRG3 →	+0.392	+3.927	<.001	.004	3	1
BLOOD_Lymphoma	HTR2C →	+0.399	+4.247	.007	.006	3	1
BLOOD_Lymphoma	ZIC3 →	+0.319	+4.452	<.001	.001	3	1
BLOOD_Lymphoma	KCNJ6 →	+0.158	+4.142	.001	.003	3	1
BLOOD_Lymphoma	TMEM82 →	+0.015	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	ADAM18 →	+0.609	+4.321	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

PRMT3 survival (RNA) · tumor vs normal (RNA) · all PRMT3 data types