PRMT2

Across TCGA patient cohorts, PRMT2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,117 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRMT2-associated genes across cancer lineages are POLE2, KNL1, and ARHGAP11A. Each is linked with PRMT2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRMT2-to-partner and partner-to-PRMT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRMT2 versus POLE2 in OV, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT2→partner) and Y-score (partner→PRMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	POLE2 →	-0.868	-0.587	.001	.001	3	5
OV	KNL1 →	-0.950	-0.509	<.001	<.001	3	5
OV	ARHGAP11A →	-0.877	-0.495	<.001	.001	3	5
OV	CDKN3 →	-1.126	-0.512	<.001	<.001	3	4
OV	KIF18A →	-1.053	-0.642	<.001	<.001	3	4
LUAD	BUB1B →	-1.019	-0.245	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,117 associations by consensus.

PRMT2 vs POLE2 — OV

Explore this scatter interactively →