PRMT1

Across TCGA patient cohorts, PRMT1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,263 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRMT1-associated genes across cancer lineages are BCL2L12, TOMM40, and GRWD1. Each is linked with PRMT1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PRMT1-to-partner and partner-to-PRMT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRMT1 versus BCL2L12 in BRCA, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT1→partner) and Y-score (partner→PRMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BCL2L12 →	+0.800	+0.375	<.001	<.001	3	9
HNSC	TOMM40 →	+0.773	+0.287	<.001	<.001	3	9
HNSC	GRWD1 →	+0.544	+0.283	<.001	<.001	3	8
GBM	LIG1 →	+0.819	+0.510	<.001	<.001	3	8
HNSC	UBE2M →	+0.714	+0.228	.005	.007	3	8
BRCA	TROAP →	+1.071	+0.279	<.001	.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,263 associations by consensus.

PRMT1 vs BCL2L12 — BRCA

Explore this scatter interactively →