PRMT1

Across TCGA cell cohorts, PRMT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,568 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRMT1-associated GO terms across cancer lineages are Nucleolar large rRNA transcription by RNA polymerase I, Transcription initiation at RNA polymerase I promoter, and Nucleosome disassembly. Each is linked with PRMT1 in more than 17 cancer types. Because this analysis shows association rather than direction, both PRMT1-to-partner and partner-to-PRMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleolar large rRNA transcription by RNA polymerase I grouped by PRMT1-low versus PRMT1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRMT1→partner) and Y-score (partner→PRMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nucleolar large rRNA transcription by RNA polymerase I →	+0.126	+0.674	.002	.004	3	18
LARGE_INTESTINE	Transcription initiation at RNA polymerase I promoter →	+0.125	+0.753	<.001	<.001	3	18
LARGE_INTESTINE	Nucleosome disassembly →	+0.165	+0.889	<.001	<.001	3	17
BLOOD_Myeloma	rRNA processing →	+0.110	+1.049	<.001	.006	3	17
PANCREAS	Termination of RNA polymerase III transcription →	+0.105	+0.940	<.001	<.001	3	17
BONE	rRNA metabolic process →	+0.122	+0.796	.006	.008	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,568 associations by consensus.

Nucleolar large rRNA transcription by RNA polymerase I by PRMT1 expression — OESOPHAGUS

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