PRM3

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PRM3 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated PRM3 data layer compared with 13 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PRM3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PRM3 expression acts as an unfavorable survival marker.

COAD are the cancer types where PRM3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSMedianII,III,IV0.5560.850.0273view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

PRM3–COAD (OS)

Kaplan–Meier survival curve for PRM3 mutant vs wild-type samples in COAD.

Open the COAD breakdown →

Exploration