PRM3

Across TCGA patient cohorts, PRM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,235 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRM3-associated GO terms across cancer lineages are Regulation of protein serine/threonine kinase activity, Mitochondrial membrane organization, and Endoplasmic reticulum organization. Each is linked with PRM3 in more than 9 cancer types. Because this analysis shows association rather than direction, both PRM3-to-partner and partner-to-PRM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein serine/threonine kinase activity grouped by PRM3-low versus PRM3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRM3→partner) and Y-score (partner→PRM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein serine/threonine kinase activity →	+0.057	+0.114	<.001	<.001	3	10
STAD	Mitochondrial membrane organization →	+0.075	+0.110	<.001	<.001	3	9
STAD	Endoplasmic reticulum organization →	+0.071	+0.120	<.001	<.001	3	9
STAD	Carbohydrate biosynthetic process →	+0.046	+0.124	<.001	<.001	3	9
STAD	Ribosome assembly →	+0.087	+0.128	<.001	<.001	3	8
STAD	DNA modification →	+0.060	+0.137	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,235 associations by consensus.

Regulation of protein serine/threonine kinase activity by PRM3 expression — STAD

Explore this box plot interactively →