PRM2

Across TCGA patient cohorts, PRM2 protein abundance is significantly associated with the RNA expression of many other genes, with 339 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRM2-associated genes across cancer lineages are HSCB, NXT2, and CD9. Each is linked with PRM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRM2-to-partner and partner-to-PRM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRM2 versus HSCB in GBM, with a Pearson correlation of -0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRM2→partner) and Y-score (partner→PRM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HSCB →	-0.520	-0.891	.002	.003	3	1
GBM	NXT2 →	-0.858	-0.550	.001	.007	3	1
GBM	CD9 →	-0.831	-0.756	.003	.004	3	1
GBM	BNIP3L →	-0.733	-0.898	.004	.002	3	1
GBM	SUSD1 →	+0.932	+0.673	.004	.002	3	1
GBM	APBA1 →	+0.991	+0.896	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 339 associations by consensus.

PRM2 vs HSCB — GBM

Explore this scatter interactively →