PRM2

Across TCGA cell cohorts, PRM2 RNA expression is significantly associated with the mutation status of many other genes, with 77 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRM2-associated genes across cancer lineages are NFE2L2, NEK1, and RFC1. Each is linked with PRM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRM2-to-partner and partner-to-PRM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NFE2L2 grouped by PRM2-low versus PRM2-high in URINARY_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRM2→partner) and Y-score (partner→PRM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	NFE2L2 →	+5.087	+0.096	.004	<.001	3	2
BLOOD_Leukemia	NEK1 →	+4.384	+0.033	.006	<.001	3	2
BLOOD_Leukemia	RFC1 →	+4.969	+0.042	.003	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	NCAM2 →	+4.209	+0.053	.006	<.001	3	2
PANCREAS	LCA5 →	+3.584	+0.064	.001	<.001	3	1
PANCREAS	UGT1A9 →	+5.000	+0.128	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 77 associations by consensus.

NFE2L2 by PRM2 expression — URINARY_TRACT

Explore this box plot interactively →