PRLH

Across TCGA patient cohorts, PRLH RNA expression is significantly associated with the go_rna of many other GO terms, with 6,615 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PRLH-associated GO terms across cancer lineages are ATP metabolic process, Proton transmembrane transport, and Mitochondrial electron transport, NADH to ubiquinone. Each is linked with PRLH in more than 9 cancer types. Because this analysis shows association rather than direction, both PRLH-to-partner and partner-to-PRLH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP metabolic process grouped by PRLH-low versus PRLH-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRLH→partner) and Y-score (partner→PRLH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	ATP metabolic process →	+0.045	+0.176	<.001	.004	2	10
ESCA	Proton transmembrane transport →	+0.044	+0.172	<.001	<.001	3	8
STAD	Mitochondrial electron transport, NADH to ubiquinone →	+0.055	+0.138	<.001	.007	1	10
ESCA	Methylglyoxal metabolic process →	+0.044	+0.166	<.001	<.001	2	9
ESCA	Positive regulation of low-density lipoprotein receptor activity →	+0.052	+0.169	<.001	<.001	3	8
STAD	Cardiolipin biosynthetic process →	+0.034	+0.226	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,615 associations by consensus.

ATP metabolic process by PRLH expression — STAD

Explore this box plot interactively →