PRLH

Across TCGA patient cohorts, PRLH protein abundance is significantly associated with the RNA expression of many other genes, with 8,239 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRLH-associated genes across cancer lineages are TWIST2, CSF2RB, and MYO1G. Each is linked with PRLH in more than 3 cancer types. Because this analysis shows association rather than direction, both PRLH-to-partner and partner-to-PRLH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRLH versus TWIST2 in UCEC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRLH→partner) and Y-score (partner→PRLH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TWIST2 →	+1.631	+1.056	<.001	.001	3	4
OV	CSF2RB →	+0.935	+1.069	.001	.004	3	3
OV	MYO1G →	+0.655	+1.512	.001	<.001	3	3
OV	DOK2 →	+0.824	+1.028	.001	.005	3	3
UCEC	SNAI2 →	+1.299	+1.083	.001	.004	3	3
UCEC	MYL9 →	+1.358	+1.268	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,239 associations by consensus.

PRLH vs TWIST2 — UCEC

Explore this scatter interactively →