PRLH

Across TCGA patient cohorts, PRLH mutation is significantly associated with the RNA expression of many other genes, with 96 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PRLH-associated genes across cancer lineages are UBE2V1P6, RN7SL470P, and MIR132. Each is linked with PRLH in more than 1 cancer types. Because this analysis shows association rather than direction, both PRLH-to-partner and partner-to-PRLH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBE2V1P6 grouped by PRLH-low versus PRLH-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRLH→partner) and Y-score (partner→PRLH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	UBE2V1P6 →	+0.108	+5.099	<.001	.008	3	2
UCEC	RN7SL470P →	+0.448	+4.279	<.001	.008	3	1
UCEC	MIR132 →	+0.850	+4.771	<.001	.006	3	1
UCEC	LINC01897 →	+0.277	+4.326	.002	.007	3	1
UCEC	DUXAP3 →	+0.425	+4.525	<.001	.005	3	1
SKCM	NOX3 →	+0.224	+4.096	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

UBE2V1P6 by PRLH expression — LUAD

Explore this box plot interactively →