PRLH

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PRLH RNA expression is significantly associated with the mutation status of many other genes, with 33 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PRLH-associated genes across cancer lineages are NCAM2, TLR6, and IARS2. Each is linked with PRLH in more than 1 cancer types. Because this analysis shows association rather than direction, both PRLH-to-partner and partner-to-PRLH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NCAM2 grouped by PRLH-low versus PRLH-high in BLOOD_Myeloma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRLH→partner) and Y-score (partner→PRLH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaNCAM2 →+4.807+0.640.006<.00131
BLOOD_MyelomaTLR6 →+4.807+0.640.006<.00131
BLOOD_MyelomaIARS2 →+4.807+0.640.006<.00131
PANCREASHSPG2 →+4.029+0.162.007<.00131
BLOOD_MyelomaAPLP1 →+4.807+0.640.006<.00131
BLOOD_MyelomaTAF1L →+4.807+0.640.006<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

NCAM2 by PRLH expression — BLOOD_Myeloma

Box plot of NCAM2 in PRLH-low vs PRLH-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration