Across TCGA pan-cancer cohorts, PRKX mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PRKX data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PRKX mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PRKX expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

CCRCC, GBM, and LSCC are the cancer types where PRKX mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	II,III,IV	0.972	0.329	.020	6	view →
GBM	DFS	Quartile	All	0.614	0.253	.047	2	view →
LSCC	DFS	Median	All	0.999	0.910	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: PRKX tumor-vs-normal RNA expression · all PRKX data types