Across TCGA patient cohorts, PRKX protein abundance is significantly associated with the RNA expression of many other genes, with 6,521 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PRKX-associated genes across cancer lineages are PLEKHG1, PRKX-AS1, and SLA2. Each is linked with PRKX in more than 2 cancer types. Because this analysis shows association rather than direction, both PRKX-to-partner and partner-to-PRKX results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKX→partner) and Y-score (partner→PRKX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PLEKHG1 →	+1.098	+0.698	<.001	<.001	3	3
LSCC	PRKX-AS1 →	+0.872	+0.520	<.001	<.001	3	3
BRCA	SLA2 →	+0.896	+0.496	<.001	.004	3	3
BRCA	TLE6 →	-1.112	-0.670	<.001	<.001	3	3
BRCA	RCSD1 →	+1.066	+0.821	<.001	<.001	3	3
HNSC	MIR138-1 →	+3.319	+0.820	.003	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,521 associations by consensus.

Exploration

PRKX survival (RNA) · tumor vs normal (RNA) · all PRKX data types