PRKRIP1

Across TCGA pan-cancer cohorts, PRKRIP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated PRKRIP1 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PRKRIP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PRKRIP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCEC show a favorable association.

LUAD, CCRCC, and UCEC are the cancer types where PRKRIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.995	0.679	<.001	44	view →
CCRCC	OS	Median	III,IV	0.797	0.965	.028	4	view →
UCEC	DFS	Median	II,III,IV	0.881	0.535	.040	4	view →
PDAC	DFS	Median	III,IV	0.854	0.494	.009	4	view →
LSCC	OS	Tertile	All	1.000	0.954	.045	2	view →
HNSC	DFS	Median	IV	1.000	0.924	.037	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

PRKRIP1–LUAD (DFS)

Open the LUAD breakdown →