PRKG2-AS1

Across TCGA pan-cancer cohorts, PRKG2-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated PRKG2-AS1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PRKG2-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PRKG2-AS1 expression acts as an unfavorable survival marker.

LUAD, COAD, and STAD are the cancer types where PRKG2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.557	0.714	<.001	129	view →
COAD	DFS	Tertile	II,III,IV	0.470	0.674	.006	72	view →
STAD	DFS	Quartile	II,III,IV	0.208	0.390	.003	55	view →
LIHC	OS	Tertile	All	0.448	0.722	.003	54	view →
UVM	OS	Tertile	III,IV	0.037	0.815	<.001	36	view →
KIRC	DFS	Tertile	All	0.727	0.873	.004	36	view →
CESC	DFS	Tertile	III,IV	0.384	0.678	.019	36	view →
KIRP	DFS	Tertile	II,III,IV	0.040	0.765	<.001	36	view →
LUSC	OS	Tertile	III,IV	0.443	0.721	.008	27	view →
BRCA	DFS	Tertile	All	0.811	0.905	.009	24	view →
HNSC	OS	Tertile	All	0.678	0.763	.031	9	view →
THCA	OS	Tertile	II,III,IV	0.342	0.914	.025	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

PRKG2-AS1–LUAD (OS)

Open the LUAD breakdown →