PRKCZ

Across TCGA patient cohorts, PRKCZ protein abundance is significantly associated with the RNA expression of many other genes, with 15,178 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRKCZ-associated genes across cancer lineages are JAKMIP2, FAAH, and MBNL1-AS1. Each is linked with PRKCZ in more than 3 cancer types. Because this analysis shows association rather than direction, both PRKCZ-to-partner and partner-to-PRKCZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKCZ versus JAKMIP2 in LSCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCZ→partner) and Y-score (partner→PRKCZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	JAKMIP2 →	-1.064	-0.247	<.001	<.001	3	4
BRCA	FAAH →	+1.232	+0.523	<.001	<.001	3	4
HNSC	MBNL1-AS1 →	-0.467	-0.181	.001	.003	3	4
CCRCC	TRHDE →	+0.949	+0.204	.005	.004	3	4
BRCA	PRKCZ-AS1 →	+0.793	+0.426	<.001	<.001	3	4
BRCA	ERBB4 →	+1.255	+0.310	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,178 associations by consensus.

PRKCZ vs JAKMIP2 — LSCC

Explore this scatter interactively →