PRKCZ

Across TCGA cell cohorts, PRKCZ RNA expression is significantly associated with the go_rna of many other GO terms, with 3,748 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PRKCZ-associated GO terms across cancer lineages are Regulation of myoblast fusion, Glycerolipid biosynthetic process, and Establishment of epithelial cell apical/basal polarity. Each is linked with PRKCZ in more than 10 cancer types. Because this analysis shows association rather than direction, both PRKCZ-to-partner and partner-to-PRKCZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by PRKCZ-low versus PRKCZ-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCZ→partner) and Y-score (partner→PRKCZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of myoblast fusion →	+0.098	+1.490	<.001	<.001	3	11
URINARY_TRACT	Glycerolipid biosynthetic process →	+0.057	+1.683	<.001	.006	3	11
OVARY	Establishment of epithelial cell apical/basal polarity →	-0.235	-1.861	<.001	<.001	3	11
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.090	+1.195	<.001	.003	3	10
UPPER_AERODIGESTIVE_TRACT	Phospholipid biosynthetic process →	+0.040	+0.743	.005	.002	3	10
OVARY	Glycerophospholipid metabolic process →	+0.042	+1.224	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,748 associations by consensus.

Regulation of myoblast fusion by PRKCZ expression — OVARY

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